Compound Q&A
How is 1-Bromo-3-fluoro-5-methylbenzene (CAS: 202865-83-6) typically synthesized?
Answer
1-Bromo-3-fluoro-5-methylbenzene can be synthesized from bromination of 3-fluoro-5-methylbenzene using bromine in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction is typically carried out in a chlorinated solvent like dichloromethane. The yield is around 70-80%, and the selectivity towards the bromination product is high due to the ortho and para directing effects of the methyl and fluoro substituents.
About
CAS No
202865-83-6
English Name
1-Bromo-3-fluoro-5-methylbenzene
Molecular Formula
C7H6BrF
Molecular Weight
189.03 g/mol
SMILES
CC1=CC(=CC(=C1)Br)F
InChIKey
CTNFNUQREIIROB-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43
