Compound Q&A

How is (2S)-4-(Benzyloxy)-2-{[(benzyloxy)carbonyl]amino}-4-oxobutanoic acid (CAS: 3479-47-8) typically synthesized?

Answer

(2S)-4-(Benzyloxy)-2-{[(benzyloxy)carbonyl]amino}-4-oxobutanoic acid
(2S)-4-(Benzyloxy)-2-{[(benzyloxy)carbonyl]amino}-4-oxobutanoic acid (CAS: 3479-47-8) is typically synthesized via the coupling of an amino acid with a benzyl alcohol derivative under mild conditions. The reaction is catalyzed by a suitable coupling agent such as HATU or EDC. The yield can be up to 80%, and the reaction is selective, ensuring the desired product is formed.

About

CAS No 3479-47-8
English Name (2S)-4-(Benzyloxy)-2-{[(benzyloxy)carbonyl]amino}-4-oxobutanoic acid
Molecular Formula C19H19NO6
Molecular Weight 357.36 g/mol
SMILES C1=CC=C(C=C1)COC(=O)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
InChIKey VUKCNAATVIWRTF-INIZCTEOSA-N
Last Updated: 2025-09-29 09:43

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