Compound Q&A

How is 2-Bromo-3-fluorobenzoic acid (CAS: 132715-69-6) typically synthesized?

Answer

2-Bromo-3-fluorobenzoic acid
2-Bromo-3-fluorobenzoic acid is typically synthesized through the bromination of 3-fluorobenzoic acid using a brominating agent like N-bromosuccinimide (NBS) in the presence of a radical initiator such as AIBN. The reaction is performed in an inert atmosphere to prevent decomposition and yields a product with good selectivity and up to 90% yield.

About

English Name 2-Bromo-3-fluorobenzoic acid
Molecular Formula C7H4BrFO2
Molecular Weight 219.009 g/mol
SMILES C1=CC(=C(C(=C1)F)Br)C(=O)O
InChIKey KQRCBMPPEPNNDS-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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