Compound Q&A

How is 5-Bromonicotinonitrile (CAS: 35590-37-5) typically synthesized?

Answer

5-Bromonicotinonitrile
5-Bromonicotinonitrile (CAS: 35590-37-5) is commonly synthesized via the reaction of nicotinonitrile with bromine in the presence of a solvent such as acetic acid. The reaction is carried out under mild conditions, typically at room temperature, with high yield and good selectivity. Common solvents used include acetic acid and acetonitrile, with acetic acid being the more preferred choice.

About

CAS No 35590-37-5
English Name 5-Bromonicotinonitrile
Molecular Formula C6H3BrN2
Molecular Weight 183.01 g/mol
SMILES C1=C(C=NC=C1Br)C#N
InChIKey FTFFHWWIPOQCBC-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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