Compound Q&A
How is 7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 68077-26-9) typically synthesized?
Answer
7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is typically synthesized from 1-ethyl-6-fluoro-3-quinolinecarboxylic acid using chlorination. The reaction involves treatment of the quinoline derivative with chlorine gas in the presence of a suitable catalyst like aluminum chloride. The yield is generally around 70-80%, and the product is purified by recrystallization from a suitable solvent.
About
CAS No
68077-26-9
English Name
7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Molecular Formula
C12H9ClFNO3
Molecular Weight
269.66 g/mol
SMILES
CCN1C=C(C(=O)C2=CC(=C(C=C21)Cl)F)C(=O)O
InChIKey
WNNSMMJBBOPPOT-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06
