Compound Q&A
How is 1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl]-1-butanone (CAS: 548-73-2) typically synthesized?
Answer
![1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl]-1-butanone](https://static.chemtradehub.com/structs/548/548-73-2-e5d5.webp "1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl]-1-butanone")
This compound is typically synthesized via a multistep process starting from 4-fluoroaniline and 2-hydroxy-1H-benzimidazol-1-yl-3,6-dihydropyridine. The synthesis involves condensation reactions, cyclizations, and purification steps. Common catalysts and reagents include triphenylphosphine and acetic anhydride.
About
CAS No
548-73-2
English Name
1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl]-1-butanone
Molecular Formula
C22H22FN3O2
Molecular Weight
379.44 g/mol
SMILES
C1CN(CC=C1N2C3=CC=CC=C3NC2=O)CCCC(=O)C4=CC=C(C=C4)F
InChIKey
RMEDXOLNCUSCGS-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06
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