Compound Q&A

How is 1,1,3,3-Tetramethyl-2-[3-(trimethoxysilyl)propyl]guanidine (CAS: 69709-01-9) typically synthesized?

Answer

1,1,3,3-Tetramethyl-2-[3-(trimethoxysilyl)propyl]guanidine
1,1,3,3-Tetramethyl-2-[3-(trimethoxysilyl)propyl]guanidine is typically synthesized via a multi-step process involving the condensation of 3-trimethoxysilylpropylamine with tetramethylguanidine. The reaction is catalyzed by concentrated hydrochloric acid, and the product is purified by recrystallization from hot ethanol. The overall yield is around 70-80%.

About

CAS No 69709-01-9
English Name 1,1,3,3-Tetramethyl-2-[3-(trimethoxysilyl)propyl]guanidine
Molecular Formula C11H27N3O3Si
Molecular Weight 277.44 g/mol
SMILES CN(C)C(=NCCC[Si](OC)(OC)OC)N(C)C
InChIKey ZUEIRGBMFHHKAC-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06

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