Compound Q&A

How is 2-Hydroxy-5-methylisophthalaldehyde (CAS: 7310-95-4) typically synthesized?

Answer

2-Hydroxy-5-methylisophthalaldehyde
2-Hydroxy-5-methylisophthalaldehyde (CAS: 7310-95-4) can be synthesized via the condensation of 5-methylisophthaldehyde and hydroxyacetone in the presence of a strong base like sodium hydroxide. The reaction is typically carried out in an aprotic solvent like dimethyl sulfoxide (DMSO) under reflux. The yield is around 85%, and the product can be purified by recrystallization from ethanol.

About

CAS No 7310-95-4
English Name 2-Hydroxy-5-methylisophthalaldehyde
Molecular Formula C9H8O3
Molecular Weight 164.16 g/mol
SMILES CC1=CC(=C(C(=C1)C=O)O)C=O
InChIKey ZBOUXALQDLLARY-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09

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