Compound Q&A

How is 2-Chloro-5-pyrimidinamine (CAS: 56621-90-0) typically synthesized?

Answer

2-Chloro-5-pyrimidinamine
2-Chloro-5-pyrimidinamine can be synthesized via the reaction of 5-chloropyrimidin-2-amine with a secondary amine under basic conditions. The process involves the use of a catalyst such as sodium hydroxide (NaOH) and is typically carried out in an aqueous solution. The reaction provides good yield and selectivity, making it a reliable method for preparing this compound.

About

CAS No 56621-90-0
English Name 2-Chloro-5-pyrimidinamine
Molecular Formula C4H4ClN3
Molecular Weight 129.55 g/mol
SMILES C1=C(C=NC(=N1)Cl)N
InChIKey DZBKIOJXVOECRA-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09

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