How is 1H-Benzo[de]isoquinoline-1,3(2H)-dione (CAS: 81-83-4) typically synthesized?

1H-Benzo[de]isoquinoline-1,3(2H)-dione is usually synthesized via the oxidative cleavage of 2,3-dihydro-1H-benzo[de]isoquinoline or by the condensation of 1,3-diketone with 1H-benzo[de]isoquinoline. The synthesis often involves the use of reagents like p-toluenesulfonic acid or potassium permanganate, with yields typically ranging from 50% to 70%. The method is selective and efficient.