Compound Q&A
How is 1-Bromo-2-fluoro-4-(trifluoromethyl)benzene (CAS: 40161-54-4) typically synthesized?
Answer
1-Bromo-2-fluoro-4-(trifluoromethyl)benzene can be synthesized via bromination of 2-fluoro-4-(trifluoromethyl)benzene using N-bromosuccinimide (NBS) in the presence of a radical initiator, such as azobisisobutyronitrile (AIBN). The reaction is typically carried out under UV light or heat to achieve a yield of approximately 70–80%.
About
CAS No
40161-54-4
English Name
1-Bromo-2-fluoro-4-(trifluoromethyl)benzene
Molecular Formula
C7H3BrF4
Molecular Weight
243 g/mol
SMILES
C1=CC(=C(C=C1C(F)(F)F)F)Br
InChIKey
XCTQZIUCYJVRLJ-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09
