Compound Q&A
How is 3-Chloro-4-Fluorobenzoic Acid (CAS: 403-16-7) typically synthesized?
Answer
3-Chloro-4-Fluorobenzoic Acid (CAS: 403-16-7) can be synthesized through the chlorination of 4-fluorobenzoic acid using thionyl chloride, followed by recrystallization. This process provides a yield of about 85-90% with good selectivity. The reaction is typically carried out under anhydrous conditions to avoid side reactions.
About
CAS No
403-16-7
English Name
3-Chloro-4-Fluorobenzoic Acid
Molecular Formula
C7H4ClFO2
Molecular Weight
174.558 g/mol
SMILES
C1=CC(=C(C=C1C(=O)O)Cl)F
InChIKey
PKTSBFXIHLYGEY-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09
