Compound Q&A
How is 2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzonitrile (CAS: 675126-27-9) typically synthesized?
Answer
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2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzonitrile is typically synthesized via a multistep process involving the reaction of 4-methoxy-5-hydroxybenzonitrile with morpholine followed by a propargylation reaction. The synthesis involves the use of a palladium catalyst and requires mild to moderate reaction conditions. The overall yield is around 70-75%.
About
CAS No
675126-27-9
English Name
2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzonitrile
Molecular Formula
C15H21N3O3
Molecular Weight
280.37 g/mol
SMILES
COC1=C(C=C(C(=C1)N)C#N)OCCCN2CCOCC2
InChIKey
DSPAUOALMSIBJA-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09
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