Compound Q&A

How is Mono-(6-p-toluenesulfonyl)-β-cyclodextrin (CAS: 67217-55-4) typically synthesized?

Answer

Mono-(6-p-toluenesulfonyl)-β-cyclodextrin
Mono-(6-p-toluenesulfonyl)-β-cyclodextrin (CAS: 67217-55-4) is synthesized by the reaction of 6-p-toluenesulfonyl chloride with β-cyclodextrin in the presence of a suitable base such as triethylamine. The reaction requires a neutral to slightly basic environment and typically yields a product with high purity. The process involves careful temperature and time control to ensure the desired product is formed with high selectivity and yield.

About

CAS No 67217-55-4
English Name Mono-(6-p-toluenesulfonyl)-β-cyclodextrin
Molecular Formula C49H76O37S
Molecular Weight 1289.18 g/mol
SMILES Cc1ccc(cc1)S(=O)(=O)OCC1OC2OC3C(CO)OC(OC4C(CO)OC(OC5C(CO)OC(OC6C(CO)OC(OC7C(CO)OC(OC8C(CO)OC(OC1C(O)C2O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O
InChIKey URYLJCBFCXEADB-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48

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