Compound Q&A

How is Ethyl (2E)-4-oxo-2-butenoate (CAS: 2960-66-9) typically synthesized?

Answer

Ethyl (2E)-4-oxo-2-butenoate
Ethyl (2E)-4-oxo-2-butenoate (CAS: 2960-66-9) can be synthesized through a reaction of ethyl acetoacetate with acetyl chloride in the presence of a Lewis acid catalyst such as aluminum chloride. This reaction provides high yield and good selectivity, making it a common method for industrial synthesis of this compound.

About

CAS No 2960-66-9
English Name Ethyl (2E)-4-oxo-2-butenoate
Molecular Formula C6H8O3
Molecular Weight 128.13 g/mol
SMILES CCOC(=O)C=CC=O
InChIKey SDGAEBKMHIPSAC-ONEGZZNKSA-N
Last Updated: 2025-09-25 13:48

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