Compound Q&A
How is 2-(4-Piperidinyl)-1H-benzimidazole (CAS: 38385-95-4) typically synthesized?
Answer
2-(4-Piperidinyl)-1H-benzimidazole is typically synthesized through the condensation of 4-piperidone with 1H-benzimidazole-2-carbaldehyde. The reaction is usually carried out in the presence of a catalytic amount of a Lewis acid such as aluminum trichloride. The yield is generally high, and the method is known for its good selectivity and reproducibility.
About
CAS No
38385-95-4
English Name
2-(4-Piperidinyl)-1H-benzimidazole
Molecular Formula
C12H15N3
Molecular Weight
201.27 g/mol
SMILES
C1CNCCC1C2=NC3=CC=CC=C3N2
InChIKey
HBOGHPAOOWUTLB-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
