Compound Q&A

How is (2,3-Difluorophenyl)boronic acid (CAS: 121219-16-7) typically synthesized?

Answer

(2,3-Difluorophenyl)boronic acid
(2,3-Difluorophenyl)boronic acid is commonly synthesized via the reduction of 2,3-difluorophenylboronic ester using a reducing agent like lithium aluminum hydride (LAH) in an inert solvent such as tetrahydrofuran (THF). The yield is typically around 80-90%, and the reaction is carried out under anhydrous conditions to ensure high purity.

About

English Name (2,3-Difluorophenyl)boronic acid
Molecular Formula C6H5BF2O2
Molecular Weight 157.91 g/mol
SMILES B(C1=C(C(=CC=C1)F)F)(O)O
InChIKey SZYXKFKWFYUOGZ-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48

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