Compound Q&A
How is (2-Chloro-3-pyridinyl)boronic acid (CAS: 381248-04-0) typically synthesized?
Answer
(2-Chloro-3-pyridinyl)boronic acid (CAS: 381248-04-0) is typically synthesized via the condensation of 2-chloro-3-pyridineboronic anion with a suitable alcohol or phenol. Common methods include the use of boronic acids with diisopropyl azodicarboxylate (DIAD) and triphenylphosphine (Ph3P) as a catalyst. The yield is generally high, and the reaction is known for its good regioselectivity and chemoselectivity.
About
CAS No
381248-04-0
English Name
(2-Chloro-3-pyridinyl)boronic acid
Molecular Formula
C5H5BClNO2
Molecular Weight
157.36 g/mol
SMILES
B(C1=C(N=CC=C1)Cl)(O)O
InChIKey
VRDAOVQZVXYRNH-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
