Compound Q&A
How is 2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene(E)-2,1-diazenediyl]}bis[3-oxo-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)butanamide] (CAS: 77804-81-0) typically synthesized?
Answer
![2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene(E)-2,1-diazenediyl]}bis[3-oxo-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)butanamide]](https://static.chemtradehub.com/structs/778/77804-81-0-cfb2.webp "2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene(E)-2,1-diazenediyl]}bis[3-oxo-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)butanamide]")
This compound is synthesized via a multi-step process involving diazomethane addition and benzimidazole condensation. Common synthetic methods include the use of trifluoroacetic anhydride and sodium hydride as catalysts. The reaction yields approximately 85% of the target compound with good selectivity to the desired isomer.
About
CAS No
77804-81-0
English Name
2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene(E)-2,1-diazenediyl]}bis[3-oxo-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)butanamide]
Molecular Formula
C36H32N10O8
Molecular Weight
732.71 g/mol
SMILES
CC(=O)C(C(=O)NC1=CC2=C(C=C1)NC(=O)N2)N=NC3=CC=CC=C3OCCOC4=CC=CC=C4N=NC(C(=O)C)C(=O)NC5=CC6=C(C=C5)NC(=O)N6
InChIKey
PUNNQKXGKNOLTB-MWOVFPFUSA-N
Last Updated: 2025-09-25 13:48
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