Compound Q&A
How is 1,3-Benzoxazole (CAS: 273-53-0) typically synthesized?
Answer
1,3-Benzoxazole can be synthesized via the reaction of benzoyl chloride with hydrazine or its derivatives. A common method involves the condensation of benzoyl chloride with hydrazine hydrate in the presence of a catalyst like p-toluenesulfonic acid. This process yields the 1,3-benzoxazole in good yield, and the method is known for its simplicity and reproducibility.
About
CAS No
273-53-0
English Name
1,3-Benzoxazole
Molecular Formula
C7H5NO
Molecular Weight
119.12 g/mol
SMILES
C1=CC=C2C(=C1)N=CO2
InChIKey
BCMCBBGGLRIHSE-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
