Compound Q&A

How is 1,3-Thiazole-5-carboxylic acid (CAS: 14527-41-4) typically synthesized?

Answer

1,3-Thiazole-5-carboxylic acid
1,3-Thiazole-5-carboxylic acid is commonly synthesized via the reaction of thiosemicarbazide with acetyl chloride or acetic anhydride. This method involves the condensation of thiosemicarbazide with an acylating agent, leading to the formation of the 1,3-thiazole-5-carboxylic acid with good selectivity and yield.

About

CAS No 14527-41-4
English Name 1,3-Thiazole-5-carboxylic acid
Molecular Formula C4H3NO2S
Molecular Weight 129.14 g/mol
SMILES C1=C(SC=N1)C(=O)O
InChIKey YZVFSQQHQPPKNX-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23

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