Compound Q&A
How is (3,4-Dimethoxyphenyl)boronic acid (CAS: 122775-35-3) typically synthesized?
Answer
(3,4-Dimethoxyphenyl)boronic acid (CAS: 122775-35-3) can be synthesized using the Stille coupling reaction. Typically, 3,4-dimethoxyphenyl bromide is coupled with tetrakis(triphenylphosphine)palladium(0) and (trimethylsilyl)boron triflate in the presence of a base such as triethylamine. The reaction yields a high yield of the desired product with good regioselectivity and functional group compatibility.
About
CAS No
122775-35-3
English Name
(3,4-Dimethoxyphenyl)boronic acid
Molecular Formula
C8H11BO4
Molecular Weight
181.98 g/mol
SMILES
COc1ccc(cc1OC)B(O)O
InChIKey
RCVDPBFUMYUKPB-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
