Compound Q&A
How is 2-Chloropyridine-4-boronic acid (CAS: 458532-96-2) typically synthesized?
Answer
2-Chloropyridine-4-boronic acid can be synthesized via a Stille coupling reaction, where 4-bromopyridine is reacted with chloroboronate ester in the presence of a palladium catalyst and a base. The reaction yields the target compound with good selectivity and high yield, making it a common method in organic synthesis.
About
CAS No
458532-96-2
English Name
2-Chloropyridine-4-boronic acid
Molecular Formula
C5H5BClNO2
Molecular Weight
157.37 g/mol
SMILES
B(C1=CC(=NC=C1)Cl)(O)O
InChIKey
WJYRVVDXJMJLTN-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
