Compound Q&A

How is Ethyl 2-chloro-1,3-oxazole-5-carboxylate (CAS: 862599-47-1) typically synthesized?

Answer

Ethyl 2-chloro-1,3-oxazole-5-carboxylate
Ethyl 2-chloro-1,3-oxazole-5-carboxylate can be synthesized via the reaction of 2-chloro-1,3-oxazole-5-carboxylic acid with ethyl chloromethyl ketone. This process typically involves the use of a base like sodium hydroxide and is conducted under reflux conditions. The yield is generally good, and the product is isolated by recrystallization from ethanol.

About

English Name Ethyl 2-chloro-1,3-oxazole-5-carboxylate
Molecular Formula C6H6ClNO3
Molecular Weight 175.57 g/mol
SMILES CCOC(=O)c1cnc(Cl)o1
InChIKey ZFLDTEIDAGWEEI-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23

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