Compound Q&A
How is 4-(Trifluoromethyl)nicotinamide (CAS: 158062-71-6) typically synthesized?
Answer
4-(Trifluoromethyl)nicotinamide (CAS: 158062-71-6) can be synthesized by reacting 4-chloronicotinamide with a trifluoromethylating agent such as trifluoromethyl chloroformate in the presence of a base like pyridine. The reaction is typically carried out in anhydrous conditions to enhance yield and selectivity. This compound is synthesized using common laboratory techniques and is known for its good yield and purity.
About
CAS No
158062-71-6
English Name
4-(Trifluoromethyl)nicotinamide
Molecular Formula
C7H5F3N2O
Molecular Weight
190.12 g/mol
SMILES
C1=CN=CC(=C1C(F)(F)F)C(=O)N
InChIKey
JUIWZYBJXUPIKF-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
