How is 1-(2,4-Dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5- Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one dihydrate (CAS: 7061-54-3) typically synthesized?

The compound is typically synthesized via a multi-step reaction involving the condensation of a 2,4-dihydroxy-6-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl) alcohol with a 4-hydroxyphenylacetaldehyde derivative. This process often uses a Brønsted acid catalyst, such as trifluoroacetic acid, to promote the condensation reaction with high yield and selectivity. The final step involves the dehydration of the product followed by the addition of water to form the dihydrate.