Compound Q&A

How is 2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7) typically synthesized?

Answer

2-Phenyl-2-(2-pyridinyl)acetamide
2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7) is typically synthesized via a multi-step process involving the condensation of 2-pyridinecarboxaldehyde with phenylacetamide. This reaction is catalyzed by a strong base such as sodium hydroxide, and the product is isolated by recrystallization. The yield is around 75-80%, and the process is selective and efficient.

About

CAS No 7251-52-7
English Name 2-Phenyl-2-(2-pyridinyl)acetamide
Molecular Formula C13H12N2O
Molecular Weight 212.25 g/mol
SMILES C1=CC=C(C=C1)C(C2=CC=CC=N2)C(=O)N
InChIKey PYAPITOPBTXXNJ-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23

Related Q&A

Compound Q&A

What are the physical and chemical properties of 2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7)?

2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7) is a colorless to white crystalline solid with a ...

Compound Q&A

What industries use 2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7)?

2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7) is used in pharmaceuticals for its anti-inflammat...

Compound Q&A

What precautions should be taken when handling 2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7)?

When handling 2-Phenyl-2-(2-pyridinyl)acetamide (CAS: 7251-52-7), it is essential to wear appropriat...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...