Compound Q&A
How is 1-Bromo-2-(trifluoromethoxy)benzene (CAS: 64115-88-4) typically synthesized?
Answer
1-Bromo-2-(trifluoromethoxy)benzene can be synthesized by the Friedel-Crafts alkylation of 2-(trifluoromethoxy)benzene with bromine in the presence of aluminum trichloride as a catalyst. The reaction yields a mixture of 1-bromo-2-(trifluoromethoxy)benzene and 2-bromo-1-(trifluoromethoxy)benzene. The reaction is typically conducted under anhydrous conditions to prevent side reactions.
About
CAS No
64115-88-4
English Name
1-Bromo-2-(trifluoromethoxy)benzene
Molecular Formula
C7H4BrF3O
Molecular Weight
241.01 g/mol
SMILES
C1=CC=C(C(=C1)OC(F)(F)F)Br
InChIKey
ITYCJCVRPBLODP-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
