Compound Q&A
How is 2,2,2-Trifluoro-1,1-ethanediol (CAS: 421-53-4) typically synthesized?
Answer
2,2,2-Trifluoro-1,1-ethanediol (CAS: 421-53-4) is typically synthesized via hydrogen fluoride (HF) or trifluoroacetic anhydride (TFAA) reactions. The process involves the reaction of ethylene oxide with hydrogen fluoride, followed by base-catalyzed hydrolysis. Alternatively, the direct reaction of trifluoroacetic anhydride with ethylene glycol yields the desired product with high selectivity and yield.
About
CAS No
421-53-4
English Name
2,2,2-Trifluoro-1,1-ethanediol
Molecular Formula
C2H3F3O2
Molecular Weight
116.04 g/mol
SMILES
C(C(F)(F)F)(O)O
InChIKey
VGJWVEYTYIBXIA-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21
