Compound Q&A

How is 4-(4-Pyridinyl)-1-butanol (CAS: 5264-15-3) typically synthesized?

Answer

4-(4-Pyridinyl)-1-butanol
4-(4-Pyridinyl)-1-butanol (CAS: 5264-15-3) is typically synthesized via the condensation of 4-pyridinecarboxaldehyde with 1-butanol using a base like potassium hydroxide as a catalyst. The reaction is carried out in a non-aqueous solvent such as acetonitrile at room temperature. The yield is generally around 70-80%, and the reaction is highly selective, making it a reliable method for obtaining the desired product.

About

CAS No 5264-15-3
English Name 4-(4-Pyridinyl)-1-butanol
Molecular Formula C9H13NO
Molecular Weight 151.21 g/mol
SMILES C1=CN=CC=C1CCCCO
InChIKey HFGNRLFZUNCBPF-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21

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