Compound Q&A

How is Methyl 2-bromo-2-methylpropanoate (CAS: 23426-63-3) typically synthesized?

Answer

Methyl 2-bromo-2-methylpropanoate
Methyl 2-bromo-2-methylpropanoate can be synthesized by bromination of 2-methylbutan-2-ol using N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction is typically carried out in an inert solvent like dichloromethane or toluene. The selectivity and yield of the reaction are influenced by the reaction conditions, such as temperature and solvent choice.

About

CAS No 23426-63-3
English Name Methyl 2-bromo-2-methylpropanoate
Molecular Formula C5H9BrO2
Molecular Weight 181.03 g/mol
SMILES CC(C)(C(=O)OC)Br
InChIKey PQUSVJVVRXWKDG-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21

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