Compound Q&A
How is 2,3,4-Trifluorobenzonitrile (CAS: 143879-80-5) typically synthesized?
Answer
2,3,4-Trifluorobenzonitrile (CAS: 143879-80-5) can be synthesized via alkylation of 2,3,4-trifluorobenzoic acid with hydrogen cyanide. Commonly, a phase-transfer catalyst is used to improve yield and selectivity. The reaction typically occurs at elevated temperatures and involves the formation of an intermediate salt that is further converted to the nitrile.
About
CAS No
143879-80-5
English Name
2,3,4-Trifluorobenzonitrile
Molecular Formula
C7H2F3N
Molecular Weight
157.09 g/mol
SMILES
C1=CC(=C(C(=C1C#N)F)F)F
InChIKey
KTPHYLJFAZNALV-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21
