Compound Q&A
How is 1-Phenyl-2-propyn-1-ol (CAS: 4187-87-5) typically synthesized?
Answer
1-Phenyl-2-propyn-1-ol (CAS: 4187-87-5) is typically synthesized via a Grignard reaction, where phenylmagnesium bromide is added to a propargyl halide in an inert organic solvent. This method provides good yield and selectivity. Other routes include the reduction of phenyl acetylene with sodium borohydride, followed by alcohol formation.
About
CAS No
4187-87-5
English Name
1-Phenyl-2-propyn-1-ol
Molecular Formula
C9H8O
Molecular Weight
132.16 g/mol
SMILES
C#CC(C1=CC=CC=C1)O
InChIKey
UIGLAZDLBZDVBL-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21
