Compound Q&A
How is Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (CAS: 1628047-87-9) typically synthesized?
Answer
![Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2)](https://static.chemtradehub.com/structs/162/1628047-87-9-6bcd.webp "Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2)")
Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride is synthesized through a multi-step process involving ring-opening of a cyclohexene oxide, followed by substitution reactions and hydrochlorination. Specific conditions include the use of Lewis acids as catalysts and careful control of reaction temperature and pressure to achieve high yields and selectivity.
About
CAS No
1628047-87-9
English Name
Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2)
Molecular Formula
C19H29Cl3N2
Molecular Weight
391.81 g/mol
SMILES
Clc1ccc(cc1)C1=C(CCC(C1)(C)C)CN1CCNCC1.Cl.Cl
InChIKey
KISZDCHFJKYNFW-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14
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