How is (2-Aminoethyl)phosphonic acid (CAS: 2041-14-7) typically synthesized?

(2-Aminoethyl)phosphonic acid is commonly synthesized by the condensation of ethylene diamine with phosphorus oxychloride followed by hydrolysis. This method provides good yield and selectivity. The reaction is typically carried out in an aprotic solvent like dichloromethane, and the use of a catalytic amount of acid, such as trifluoroacetic acid, enhances the reaction efficiency.