Compound Q&A

How is 2,3-Diethyl-5-methylpyrazine (CAS: 18138-04-0) typically synthesized?

Answer

2,3-Diethyl-5-methylpyrazine
2,3-Diethyl-5-methylpyrazine (CAS: 18138-04-0) is typically synthesized via the reaction of methylpyrazine with ethylmagnesium bromide followed by hydrolysis. This method provides good selectivity and moderate yield. Other routes involve the condensation of pyrazine with appropriate aldehydes or ketones in the presence of a suitable catalyst.

About

CAS No 18138-04-0
English Name 2,3-Diethyl-5-methylpyrazine
Molecular Formula C9H14N2
Molecular Weight 150.22 g/mol
SMILES CCc1c(nc(cn1)C)CC
InChIKey PSINWXIDJYEXLO-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14

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