Compound Q&A
How is 1-Bromo-3-(trifluoromethoxy)benzene (CAS: 2252-44-0) typically synthesized?
Answer
1-Bromo-3-(trifluoromethoxy)benzene is typically synthesized via bromination of 3-(trifluoromethoxy)benzene with N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction is carried out at elevated temperatures, and the product can be isolated by crystallization. This method ensures high yield and good selectivity.
About
CAS No
2252-44-0
English Name
1-Bromo-3-(trifluoromethoxy)benzene
Molecular Formula
C7H4BrF3O
Molecular Weight
241.01 g/mol
SMILES
C1=CC(=CC(=C1)Br)OC(F)(F)F
InChIKey
WVUDHWBCPSXAFN-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14