Compound Q&A

How is 1-Ethynyl-4-propylbenzene (CAS: 62452-73-7) typically synthesized?

Answer

1-Ethynyl-4-propylbenzene
1-Ethynyl-4-propylbenzene (CAS: 62452-73-7) is usually synthesized via a Grignard reaction. Propargyl bromide reacts with a methyl Grignard reagent in the presence of a suitable solvent like THF. The product is then quenched with an acid, followed by purification using distillation or recrystallization techniques. This process yields a high purity product with good selectivity and yield.

About

CAS No 62452-73-7
English Name 1-Ethynyl-4-propylbenzene
Molecular Formula C11H12
Molecular Weight 134.22 g/mol
SMILES CCCC1=CC=C(C=C1)C#C
InChIKey UVFFOABHOIMLNB-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14

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