Compound Q&A

How is Methyl 2-(4-bromophenyl)-2-methylpropanoate (CAS: 154825-97-5) typically synthesized?

Answer

Methyl 2-(4-bromophenyl)-2-methylpropanoate
Methyl 2-(4-bromophenyl)-2-methylpropanoate (CAS: 154825-97-5) can be synthesized via a bromination reaction of 2-(4-hydroxyphenyl)-2-methylpropanoic acid followed by esterification with methanol. This process often uses N-bromosuccinimide (NBS) as a brominating agent and is typically carried out at room temperature. The yield is around 80-85%, with good selectivity for the bromination step.

About

English Name Methyl 2-(4-bromophenyl)-2-methylpropanoate
Molecular Formula C11H13BrO2
Molecular Weight 257.13 g/mol
SMILES CC(C)(C1=CC=C(C=C1)Br)C(=O)OC
InChIKey JTYDXPPFLQSEAQ-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14

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