Compound Q&A

How is (2-Bromophenyl)acetonitrile (CAS: 19472-74-3) typically synthesized?

Answer

(2-Bromophenyl)acetonitrile
(2-Bromophenyl)acetonitrile can be synthesized via a reaction between phenylacetonitrile and bromine in the presence of a Lewis acid such as iron(III) bromide. This reaction selectively brominates the aromatic ring, yielding the desired product with a yield of around 70-80%. Other methods include using other brominating agents like N-bromosuccinimide (NBS) under suitable conditions.

About

CAS No 19472-74-3
English Name (2-Bromophenyl)acetonitrile
Molecular Formula C8H6BrN
Molecular Weight 17.03 g/mol
SMILES C1=CC=C(C(=C1)CC#N)Br
InChIKey BVCOJESIQPNOIF-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14

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