Compound Q&A
How is (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine (CAS: 110429-36-2) typically synthesized?
Answer
![(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine](https://static.chemtradehub.com/structs/110/110429-36-2-d7db.webp "(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine")
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine is synthesized through a multistep process involving the protection of the amine, introduction of the fluorophenyl group, and subsequent coupling with the benzodioxol moiety. The synthesis requires the use of catalysts like palladium complexes and protecting groups. The overall yield is typically around 50-60%.
About
CAS No
110429-36-2
English Name
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine
Molecular Formula
C20H22FNO3
Molecular Weight
343.4 g/mol
SMILES
CN1CCC(C(C1)COC2=CC3=C(C=C2)OCO3)C4=CC=C(C=C4)F
InChIKey
MOJZPKOBKCXNKG-YJBOKZPZSA-N
Last Updated: 2025-09-19 21:14
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