Compound Q&A

Are there alternatives to N,N-Dibutylformamide in synthesis (CAS: 761-65-9)?

Answer

N,N-Dibutylformamide
Several alternatives to N,N-Dibutylformamide can be used in synthesis depending on the specific requirements. Analogous solvents like dimethylformamide (DMF) or other lower alkyl formamides can be considered. Isomers such as N,N-dimethylformamide (DMF) or N,N-diethylformamide (DEF) can also serve as substitutes. Other common alternatives include other organic solvents like acetonitrile or dimethyl sulfoxide (DMSO) which may offer similar solvation properties. It's important to evaluate the compatibility and cost-effectiveness of each alternative.

About

CAS No 761-65-9
English Name N,N-Dibutylformamide
Molecular Formula C9H19NO
Molecular Weight 157.26 g/mol
SMILES CCCCN(CCCC)C=O
InChIKey NZMAJUHVSZBJHL-UHFFFAOYSA-N
Last Updated: 2025-09-17 14:48

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