Compound Q&A

How is 2,3-Dihydro-1,4-benzodioxin-2-yl(1-piperazinyl)methanone hydrochloride (CAS: 70918-74-0) typically synthesized?

Answer

2,3-Dihydro-1,4-benzodioxin-2-yl(1-piperazinyl)methanone hydrochloride (1:1)
2,3-Dihydro-1,4-benzodioxin-2-yl(1-piperazinyl)methanone hydrochloride (CAS: 70918-74-0) is typically synthesized by the condensation of 2,3-dihydro-1,4-benzodioxin-2-one with 1-piperazinecarboxylic acid. The reaction is usually catalyzed by a suitable base, and the product is obtained with good yield. The synthesis is carried out under mild conditions, and the product is isolated by recrystallization from an appropriate solvent.

About

CAS No 70918-74-0
English Name 2,3-Dihydro-1,4-benzodioxin-2-yl(1-piperazinyl)methanone hydrochloride (1:1)
Molecular Formula C13H17ClN2O3
Molecular Weight 284.743 g/mol
SMILES C1CN(CCN1)C(=O)C2COC3=CC=CC=C3O2.Cl
InChIKey TUKBWYXLYINULI-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49

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