Compound Q&A
How is 2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid (CAS: 83799-24-0) typically synthesized?
Answer
![2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid](https://static.chemtradehub.com/structs/837/83799-24-0-52fc.webp "2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid")
2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid is synthesized via a multi-step route involving the formation of a piperidine ring, subsequent coupling reactions, and esterification. Common synthetic methods include the use of coupling agents like HATU and selective esterification under mild conditions. The yield is typically around 70-80%, and the reaction proceeds with good selectivity.
About
CAS No
83799-24-0
English Name
2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid
Molecular Formula
C32H39NO4
Molecular Weight
501.67 g/mol
SMILES
CC(C)(C(=O)O)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4
InChIKey
RWTNPBWLLIMQHL-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49
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