Compound Q&A
How is 2-Methyl-2-propanyl (3R)-3-pyrrolidinylcarbamate (CAS: 122536-77-0) typically synthesized?
Answer
2-Methyl-2-propanyl (3R)-3-pyrrolidinylcarbamate is typically synthesized via a multi-step process involving the condensation of 2-methyl-2-propanol with 3-pyrrolidinylcarbamic acid. The reaction is performed under mild conditions using a Lewis acid catalyst, such as aluminum chloride, to promote the formation of the ester bond. The overall yield is around 70-80%, with good selectivity towards the 3R-enantiomer.
About
CAS No
122536-77-0
English Name
2-Methyl-2-propanyl (3R)-3-pyrrolidinylcarbamate
Molecular Formula
C9H18N2O2
Molecular Weight
186.25 g/mol
SMILES
CC(C)(C)OC(=O)NC1CCNC1
InChIKey
DQQJBEAXSOOCPG-SSDOTTSWSA-N
Last Updated: 2025-09-16 13:49
