How is 1-{[(4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-arginylglycinamide (CAS: 16679-58-6) typically synthesized?

This compound can be synthesized through a multi-step process involving the coupling of amino acids and cyclic peptides. Key steps include the formation of amide bonds and the introduction of the specific substituents such as amino and hydroxy groups. The synthesis typically requires the use of protecting groups to control reactivity and ensure selective modifications. High-yield methods often involve the use of solid-phase synthesis with appropriate catalysts and solvents.