Compound Q&A
How is Evans blue (CAS: 314-13-6) typically synthesized?
Answer
Evans blue (CAS: 314-13-6) is synthesized from 4,4'-diamino-3,3'-diethylbenzidine and hydroxyquinoline. The reaction involves a condensation step followed by sulfonation, which yields the characteristic blue dye. The process requires careful control of pH and temperature to ensure high yield and selectivity.
About
CAS No
314-13-6
English Name
Evans blue
Molecular Formula
C34H24N6Na4O14S4
Molecular Weight
960.8 g/mol
SMILES
CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C3)C(=CC(=C4N)S(=O)(=O)[O-])S(=O)(=O)[O-])O)C)N=NC5=C(C6=C(C=C5)C(=CC(=C6N)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+].[Na+].[Na+]
InChIKey
ATNOAWAQFYGAOY-UHFFFAOYSA-J
Last Updated: 2025-09-16 13:49
