Compound Q&A
How is Halometasone (CAS: 50629-82-8) typically synthesized?
Answer
Halometasone (CAS: 50629-82-8) is synthesized through a series of steps starting from 17-hydroxyprogesterone. The process involves alkylation, reduction, and esterification reactions. Key reagents include methyl bromide, sodium borohydride, and acetic anhydride. The yield is typically around 75-80%, and the product is purified by recrystallization from ethanol.
About
CAS No
50629-82-8
English Name
Halometasone
Molecular Formula
C22H27ClF2O5
Molecular Weight
444.9 g/mol
SMILES
CC1CC2C3CC(C4=CC(=O)C(=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C)Cl)F
InChIKey
GGXMRPUKBWXVHE-MIHLVHIWSA-N
Last Updated: 2025-09-16 13:49
