Compound Q&A

How is 2-sec-Butylphenol (CAS: 89-72-5) typically synthesized?

Answer

2-sec-Butylphenol
2-sec-Butylphenol is typically synthesized through the reaction of sec-butyl chloride with phenol in the presence of a base such as sodium hydroxide. The reaction is carried out in an aqueous medium, and the product is isolated by acidification and extraction. Commonly used catalysts include potassium hydroxide. The yield is usually around 80-90%, with high selectivity towards 2-sec-Butylphenol.

About

CAS No 89-72-5
English Name 2-sec-Butylphenol
Molecular Formula C10H14O
Molecular Weight 150.22 g/mol
SMILES CCC(C)c1ccccc1O
InChIKey NGFPWHGISWUQOI-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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