Compound Q&A
How is (3R)-Quinuclidin-3-ol (CAS: 25333-42-0) typically synthesized?
Answer
(3R)-Quinuclidin-3-ol (CAS: 25333-42-0) can be synthesized via the reduction of (3R)-quinuclidine-3-one using sodium borohydride or lithium aluminium hydride. Another method involves the condensation of methyl glyoxylate and 3,3-dimethyl-1-azabicyclo[2.2.1]heptane followed by an acid-catalyzed hydrolysis. Yield and selectivity can be optimized by adjusting the conditions.
About
CAS No
25333-42-0
English Name
(3R)-Quinuclidin-3-ol
Molecular Formula
C7H13NO
Molecular Weight
127.18699999999997 g/mol
SMILES
C1CN2CCC1C(C2)O
InChIKey
IVLICPVPXWEGCA-ZETCQYMHSA-N
Last Updated: 2025-09-13 09:53
